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Thirman, Michael J.
One or more keywords matched the following items that are connected to Thirman, Michael J.
Item TypeName
Concept Proto-Oncogene Proteins
Concept Oncogene Proteins, Fusion
Concept Oncogene Proteins v-myb
Concept Proto-Oncogene Proteins c-pim-1
Concept Proto-Oncogene Proteins c-kit
Concept Proto-Oncogene Proteins c-bcl-6
Academic Article The human programmed cell death-2 (PDCD2) gene is a target of BCL6 repression: implications for a role of BCL6 in the down-regulation of apoptosis.
Academic Article Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice.
Academic Article ELL and EAF1 are Cajal body components that are disrupted in MLL-ELL leukemia.
Academic Article ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties.
Academic Article The elongation domain of ELL is dispensable but its ELL-associated factor 1 interaction domain is essential for MLL-ELL-induced leukemogenesis.
Academic Article The human BCL6 transgene promotes the development of lymphomas in the mouse.
Academic Article Repression of the PDCD2 gene by BCL6 and the implications for the pathogenesis of human B and T cell lymphomas.
Academic Article Gene mutations, epigenetic dysregulation, and personalized therapy in myeloid neoplasia: are we there yet?
Academic Article PDCD2, a protein whose expression is repressed by BCL6, induces apoptosis in human cells by activation of the caspase cascade.
Academic Article PIM1 gene cooperates with human BCL6 gene to promote the development of lymphomas.
Academic Article Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias.
Academic Article EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein.
Academic Article MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome.
Academic Article GFI1B, EVI5, MYB--additional genes that cooperate with the human BCL6 gene to promote the development of lymphomas.
Academic Article Instructive Role of MLL-Fusion Proteins Revealed by a Model of t(4;11) Pro-B Acute Lymphoblastic Leukemia.
Academic Article The full transforming capacity of MLL-Af4 is interlinked with lymphoid lineage commitment.
Academic Article Quercetin Therapy for Selected Patients with PIM1 Kinase-Positive Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: A Pilot Study.
Academic Article Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis.
Academic Article Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia.
Academic Article The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia.
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  • Oncogene Proteins